Aikaterini Skokotas
I
am an Associate Professor of Biology and I have been a faculty member
at Rosemont College since the fall of 1997. I was awarded tenure, June
2011. I was awarded the Lindback Award for Distinguished teaching in
2008. I have been the Discipline Chair of the department since 2002 and
have also served as the Division chair. I received my BA degree from
Rutgers University in Biology (1989) and my Ph.D. from Drexel University
(1995). The title of my Ph.D. thesis is “The isolation and
characterization of mutants of Tus, the replication arrest protein of E.
coli and the identification of its replication arrest domain”. I have
also completed a two year post-doctoral fellowship (1995-97) at the
Wistar Institute in Philadelphia. This research examined the use of the
Herpes Simplex Virus on treating brain tumors. Currently, my research
examines the regulation of meiosis in the yeast, S. cerevisiae. This
work is being conducted in collaboration with Dr. Edward Winter at
Thomas Jefferson University and has allowed me to involve our
undergraduate students to conduct research in my laboratory at Rosemont.
As a result of this work, twelve students have conducted research in my
lab and they have presented their work in numerous local and national
meetings (see list attached). Two of these presentations received awards
(see below). It has also led to two recent publications in the journal
of Molecular Cell Biology and the Proceedings of the Annual Conference for Biology Laboratory Education (see below).
My
teaching areas include cell and molecular genetics. Currently, I teach
the following courses at Rosemont College: Life Science I lecture and
laboratory, Genetics lecture and laboratory, Microbiology lecture and
laboratory, Molecular Genetics lecture and laboratory, Immunology,
Virology, Senior Seminar and Undergraduate Research. In the past, I have
also taught Science Issues lecture and Lab (a course for non-majors),
Life Science II lecture (general biology courses for majors), Advanced
Experimental Biology and Senior Seminar II. During the summer, I also
teach a graduate level course, Medical Microbiology at Arcadia
University which supports their Physician Assistant Program.
PUBLICATIONS:
- Marcus Shin, Aikaterini Skokotas
and Edward Winter (2010). The Cdk1 and Ime2 Protein Kinases Trigger
Exit from Meiotic Prophase in Saccharomyces
- cerevisiae by Inhibiting the Sum1 Repressor, Molecular Cell Biology, 30, 1682
- Aikaterini
Skokotas and Edward Winter (2010). Regulation of meiosis in S.
cerevisiae., Tested Studies for Laboratory Teaching, the Proceedings of
the Annual Conference for Biology Laboratory Education, Volume 31
- A. Skokotas and D.M. Ratterman (2007). Molecular techniques used in comparative studies of organisms. SEPCHE e-Packet.
- R.
Tal-Singer, W. Podrzucki, T.M. Lasner and A. Skokotas, and J.J. Leary
(1998). Use of differential display reverse transcription-PCR to reveal
cellular changes during stimuli that result in herpes simplex virus type
1 reactivation from latency: upregulation of immediate-early cellular
response genes TIS7, interferon and interferon regulatory factor-1.
Journal of Virology 72, 1252
- R. Tal-Singer, T.M. Lasner; W.
Prodrzucki, A. Skokotas, J.J. Leary, S.L. Berger and N.W. Fraser (1997).
Gene expression during reactivation of herpes simplex virus type 1 from
latency in the peripheral nervous system is different from that during
lytic infection of tissue cultures. Journal of Virology 71, 5268
- A.
Skokotas, H. Hiasa, K. Marians, L. O'Donnell and T. M. Hill (1995).
Mutations in the E. coli Tus protein define a domain positioned close to
the DNA in the Tus-Ter complex. J. Biol. Chem. 270, 30941.
- A.
Skokotas, M. Wrobleski and T. M. Hill. (1994) Isolation and
characterization of mutants of Tus, the replication arrest protein of E.
coli. J. Biol. Chem. 269, 20446.
- F.F. Coskun-Ari, A.
Skokotas, G. R. Moe, and T. M. Hill (1994). Biophysical characteristics
of Tus, the replication arrest protein of E. coli. J. Biol. Chem. 269,
4027
PRESENTATIONS:
- Winifed
Wolfe, Aikaterini Skokotas, and Edward Winter (2011). Analysis of
meiotic commitment using a GFP tagged protein in S. cerevisiae,
Discovery Research Day, Drexel University College of Medicine, Poster 17
- Winifed
Wolfe, Marcus Shin, Volodymyr Yefymenko, Edward Winter and Aikaterini
Skokotas (2011). Assessing the role of Sum1 mutants in the meiotic
development of S. cerevisiae, 13th Annual SEPCHE Honors Conference,
Cabrini College, Session I-I
- Hizamar Ponce, Winifred Wolfe,
Tetyana Churyi, Ameema Hashmi, Edward Winter and Aikaterini Skokotas
(2011). Assessing the role of Hst1 sirtuin in meiotic development in S.
cerevisiae, 87th Annual Meeting of the Pennsylvania Academy of Science,
Penn State University Altoona, Altoona, poster 154
- Annie Wu,
Jeffy Mathew, Hizamar Ponce, Winifred Wolfe, Edward Winter and
Aikaterini Skokotas (2011). Assessing the role of Hst1 sirtuin in
meiotic development in S. cerevisiae, Joseph’s University Sigma Xi
Student Research Symposium, Poster 61
- Tetyana Churiy, Ameema
Hashmi, Hizamar Ponce, Winifred Wolfe, Edward Winter and Aikaterini
Skokotas (2010). Assessing the role of the Hst1 Sirtuin in the meiotic
development of S. cerevisiae, Undergraduate Research Symposium,
University of Maryland Baltimore Campus, Poster 71
- Marcus Shin,
Aikaterini Skokotas, and Edward Winter (2010) The Cdk1 and Ime2 protein
kinases trigger exit from meiotic prophase by inhibiting the Sum1
transcriptional repressor. Annual Yeast Genetics and Molecular Biology
Meeting, University of British Columbia, BC Canada, poster 233C
- Aikaterini Skokotas (2010). “Medical Advances of the Decade”, Rosemont College, Reunion Weekend.
- Aikaterini
Skokotas, (2010). “The Century of Biology: The Human Genome Project and
Beyond” Presentation at SEPCHE summer course, Rosemont College
- Fizza
Hashmi, Disha Shah, Marcus Shin, Noreen Ahmed, Edward Winter and
Aikaterini Skokotas (2010). Analysis of sum-1 regulation by Cdk1 during
meiosis in S. cerevisiae. St. Joseph’s University Sigma Xi Student
Research Symposium, Poster 47
- Disha Shah, Fizza Hashmi, Marcus
Shin, Noreen Ahmed, Edward Winter and Aikaterini Skokotas (2010).
Analysis of sum-1 regulation by Cdk1 during meiosis in S. cerevisiae.
Thomas Jefferson University Sigma Xi Student Research Day, poster 44
(AWARD WINNER)
- Disha Shah, Fizza Hashmi, Marcus Shin, Noreen
Ahmed, Edward Winter and Aikaterini Skokotas (2010). ). Sites involved
in Meiotic regulation in S. cerevisiae. 12th Annual SEPCHE Honors
Conference, Arcadia University, Session II, IIA
- Winifred Wolfe
and Nidha Azam (2010). Glucose regulation of meiosis in S. cerevisiae
via PKA. 12th Annual SEPCHE Honors Conference, Arcadia University,
Session I, IA
- Winnie Wolfe, Nidha Azam and Aikaterini Skokotas
(2009). Regulation of meiosis in S. cerevisiae via PKA. Undergraduate
Research Symposium, University of Maryland Baltimore Campus, Poster 48
(AWARD WINNER)
- Aikaterini Skokotas and Edward Winter (2009).
Regulation of meiosis in S. cerevisiae via PKA. Annual Conference of the
Association for Biology Laboratory Education, University of Delaware.
Abstract No. 23
- M. Mathew, A. Skokotas and E. Winter (2009).
Regulation of meiosis in S. cerevisiae via PKA. Sigma Xi Research
Symposium, St. Joseph’s University, poster 71
- Aikaterini
Skokotas (2009). A Mendelian genetics web-based interactive biology
laboratory simulation. The SouthEastern Pennsylvania Consortium for
Higher Education (SEPCHE) Faculty Development Conference, Lafayette
Hill, PA
- Aikaterini Skokotas, (2009). “The Century of Biology:
The Human Genome Project and Beyond”, Keynote presentation at Academic
Honors day, Rosemont College
- Charles R. Daniels, Neeti Bathala,
and Aikaterini Skokotas (2006). Molecular techniques used in comparative
studies of organisms. SEPCHE Institute for Mathematics and Science
Conference, Immaculata University, poster
- A. Skokotas, S.
Kesari, B. Randazzo, M.S. Brown and N.W. Fraser (1996). "Studies of
reactivation of HSV-1 by the superinfection of a second HSV-1 strain",
21st Herpesvirus Workshop, Northern Illinois University, DeKalb,
Illinois, Abstract No. 487
- A. Skokotas, M. Wrobleski, and T. M.
Hill (1994). "Isolation and characterization of mutants of Tus, the
replication arrest protein of E. coli", Cold Spring Harbor Conference on
Molecular Genetics of Bacteria and Phage, University of Wisconsin,
Madison, Wisconsin, Abstract No. 226
- F. F Coskun-Ari, A.
Skokotas and T. M. Hill (1992). "Physical and biochemical properties of
the E. coli Tus protein", Keystone Symposia on Molecular and Cellular
Biology, Taos, New Mexico, Abstract No. F311.
- A. Skokotas and T.
M. Hill (1991). "Characterization of Tus protein in E. coli by
mutational analysis", Scientific Research Symposium, Drexel University,
Philadelphia, PA, Abstract No.
AWARDS & HONORS
- Awarded Tenure, June 2011
- Connelly Faculty Development Grant, 2010
- Poster presentation received an award in the Undergraduate Section, (2010) Disha Shah, Fizza Hashmi, Marcus Shin, Noreen Ahmed, Edward Winter and Aikaterini Skokotas. Analysis of sum-1 regulation by Cdk1 during meiosis in S. cerevisiae. Thomas Jefferson University Sigma Xi Student Research Day, poster 44
- Promotion to Associate Professor, 2009
- Connelly Faculty Development Grant, 2009
- Poster presentation received an award in the Biological Science Section, (2009) Winifred Wolfe, Nidha Azam and Aikaterini Skokotas. Regulation of meiosis in S. cerevisiae via PKA. Undergraduate Research Symposium, University of Maryland Baltimore Campus, poster 48
- Lindback Award, Rosemont College, 2008
- Connelly Young Faculty Grant, 2007
- Post-Doctoral Training Grant, The Wistar Institute, 1996
- Research Assistantship, Drexel University (1990-1994, 1994-1995)
- Teaching Assistantship, Drexel University (1989-1990, 1994-1994)
- Dean's List, Rutgers University (1987-1989)